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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c76aed4e147f964c643b1689c115df4779a03b1bebb60b8c304f076a8752923' 
  AND token = 'OTSu7lOYMKQtXH+rDOOkohPdsfCXhlx0vp/15Pgx49Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}