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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dc052ebbdaebeea0ea9d6f7a8ba35dde196ee70bec6f46171d66ef500ff6654' 
  AND token = '07O5+5yG1pF1w5PiTqyjQWrzkcZpsJhryd7I6aBDj5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}