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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2601b959710e6c8ed04a2f6734908a4e9faf2b3850f3a948a708f65efd39065f' 
  AND token = 'cUhbEtVaiZ9cim89K/IFkcGLzMeEI0+gLclTO4tc7XM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}