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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4f66f6513b241f6f66f76aacdeb273251e068bac7602cb56eff0e47171624e' 
  AND token = 'bZw5EKgtIbWpgnQdeyM1Nme4XSPotV9lywdL/LIOjw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}