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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c73e78e4c0454b692d75de43a9e795b8a2dc8c2228fbd5296b6a9d8b6f3f40a' 
  AND token = 'c8CSEVL1txMGaxZZv9MhIYIINBrBhlcYsNYEad7JTXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}