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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5a492ffbe9a325ac23b583773433c97b8a154af0a25d9f2b2ac869b6d4273a' 
  AND token = 'XEaJyd/4SA93MJRibEkfZGvg+hZmHHv6dtEo5InbTJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}