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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6326cd42d15600d2be5833918dd9ce651c5eabd15192287f172549f5232f7d' 
  AND token = 'cGVstV3yssUXWiE+SaIG8yB9ZxMwelGJzK8t5PMt4Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}