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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e537bb6b74a2536d58b87e6955857b33002119b24a6bd2ed4ca84d92014f3467' 
  AND token = 'Tq++zcy7SoNj2S4thkURN5EW41ST/7ZpppSodSla/II=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}