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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3f48b9ef278b295fa5caf940b71c690f905486a6d0f8d685dce053f073bec4' 
  AND token = 'yXH4z8aDWxACZXF4UBMF2k2WXZOESc+0AYGWQTEbS7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}