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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e8c5f35c059873bb5b2d3717227aaa5c950bf7ff35fc3afc6eb27216c047a4d' 
  AND token = '3ptZXiODk5aso/Az2i0anjbLtse2gRQki/anAj2rDTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}