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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3ec90df494692851b8724564474a1918c6acd3b54ebfd1c8ab78ec2bda3880' 
  AND token = 'cUFVDt5sxwDksgbJTOD6a1q70auAC69ymeILtJiXnFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}