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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280263e854f3e2115e159f89859241719928a91ea24300db8206273ff6fa6c7c' 
  AND token = 'WI9AnQnowPITM+/ksu7X+Iin7L4O94Rd6v3yVqXIUCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}