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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2b3b204d614ac8300d43c11dd87fba2f4825c0ca27f55d53eb41e0a1508e9a' 
  AND token = 'Y+1wrblt+1TokCKVYxcBMvxtyvomsGCfxZk/Ku4LjTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}