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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a543ce0738958eb11077038f95f5dce859f7007ed009e8b3526448feab75e50c' 
  AND token = '3XX2g9bHV1zd+9PdTb5IN2qHkjqkjKBY+Q5N/H0kjq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}