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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33787c880bfe0d1a789c7276c1ffddf0a313986f2c2c9e9d30ebcc573b46468c' 
  AND token = 'Qzjs8TGTUh7YjmxkJPhUj33Q/XKsonRGiRMc9p6w6cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}