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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a54b6dec77bea9da789745c32515ab9c5f50e79435adadf3f953486823b5a9a' 
  AND token = 'QO7ByjgmsSJHqqlG5pU46DUnqKfzZirblHqA8Lau4Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}