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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4dfa1572daf398a2875c10e84e03a23e59d24725e3e950bf1ea43d99d8c5b3d' 
  AND token = 'I1Nf7V4kW1npKVL3bh6zlwRjVZ2YWkIjXm2WXRlR/pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}