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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '177f38ad4c6254fc60a11df0dbc0cb1de3e3cb40bf4fa4c4838756d18e1cda30' 
  AND token = 'ttwFtjqrGXGb4HQ/OS4A5uBDdPdCiHUT7uYCo2YbiBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}