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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d2785e0ad9f47bd43ddd1b10c2c1d0219971f9556760fd14539861250862774' 
  AND token = 'Fa4QL3kSVUByaSrmkexKAE4SJCjLDMwnVA46mwQJdIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}