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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e576f9f6e3bf810c2759f21004dedeeabf3ee4186be9284fbb10f015da00d6e' 
  AND token = '1knyMj0WMhoIRagYHWWjwFp8Mb6kva+qFFpD7rgTFHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}