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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '622435e7ca4e63c16b55f4c0f12e2f79bbaea13e4795886c408bc5912df64bbc' 
  AND token = 'jcV1eAumUq/lljhlhKdqbTcfYoqgb5wsIPKVEHFBUcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}