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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a14b34655c448693cc3b2f64fd43b2eb826ddc8560996b7c87604e8e8a17608d' 
  AND token = 'Bzs0irGBYksgy2b37O/HNefgbKms7FoXyySpymlB6cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}