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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3e489c094ca8512eee8e7b675f77c2d5f833f048478e64480dda722f2220e3' 
  AND token = '9YWZLznF4IeZUa+G7bhv+7m8rI1HKrMMjftoNJcTYn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}