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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fc2eac840ae96a91f8f36861fd278e07182902c6ac263e854fe7c3139af9783' 
  AND token = 'Y0Z+SRs4k4VREiPHqDA37EgoXLKoCpYCuig/I5WUynU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}