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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d1823a769aab1e39f1c0506b1ca6bfb2964548827f45bf816caad4c377c077e' 
  AND token = 'UISCiIB50q5Je0KBlFQ1oAQMoy87Z2gd9DSi3EpoW20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}