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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0df9d81f2ba2280ae1c2a60798ba38656ed07ecfbf195187f2e770175ac7b7d4' 
  AND token = 'jIJeUTLcczp+zkxDexetLE4/E3qSMT3hBPqNdtudqUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}