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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddfda188013008c39eea4003bd86f68d01297141b2e55b501d9ed8fcb3e1014d' 
  AND token = '0MpsUw/ooTT0bym9kX+pI+ovqIol7EgZ4kP1zB2uw4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}