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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3d18be6d9d637f7ea59712e02078b2f1884c07a6283a88f0b52e6fc82d24b6' 
  AND token = '8Pp0iEFheFepMABcUTTg9I2Q1XzV0EhsBCPz3U3jQlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}