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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fee8d4a5054be5d2773cc17b675663c13e61fdbdf2a485d466e6fb931240f7b' 
  AND token = 'v7Nr1/U9homhLhf5f0oeWuTIzlxXZOBzI72wnOK3keY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}