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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df548e70c4ea5b0f42a23514b5fd77b5edd12ba405cd7ba3e376af1e985a032d' 
  AND token = 'vTASJytC1+Pk4P6DguFpXotj1KecgkGf/PokDe6NYzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}