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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5abd122fd8b29de4bc8b22da83612d036caa4898b01d41a68f7119af7c31bce1' 
  AND token = 'X1Cqg6zYuLKZx5gpW1rLXeVdQELjJy7Up5iBDinpmMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}