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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22fa81ffc5c64a9d3d90da47ebd79fe7f88f527c45a60a30b44f1bd8727ac72' 
  AND token = 'f8tT+6IOA4ZMFsJjLydULW7ltsv6+28tgC2BIR+erVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}