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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48934ae1e302fab164f42ca621eb33623c0c22c4186a030313263c6409fae271' 
  AND token = 'ni030zLGQzHKlLQ/U2tel092Lt+wcLGt/pXhDpY3IWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}