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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21eacf7ce16595d4656bc4d406c480701ac581cc00960bd5c1578188193c5a03' 
  AND token = 'fkhVGYKZsC0h0svTeYFV7Z3jG23M0/5oc5vCj1saP94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}