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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f1d9b89d39522031bf7721bd84d855d4e98b2d3d8a2158aa409567a22920491' 
  AND token = 'E7S2hEjVC1Dj8LDwvK17F2u9qMdiAsAcskb7q3SDcqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}