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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a51b3245f20b44da41789300f4bdcd73c2d717442c059522675b99740d4be433' 
  AND token = 'bMGbv+JYhZWkcbmjMwkMBva7L7jBC4A69js685DRTKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}