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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66523843f5dd4211b5168f6bfde7e9fca5b3eec041dcdec75e20c9f28e451791' 
  AND token = 'TdXJUUhN70zE1tbehSnFULatyiY+zn9PGo/xJsE9TV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}