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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8109dcd11a342a24a11ddc3fd97a5f6c76a4b26acb275d2a8f273966a5537be' 
  AND token = 'GB0pcKLyOwUyLV72E2q251HSdsvcV4MmiOiZF6u0gKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}