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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e330a799219e5230108d7a54709940c150e9e8d08f7856520bbfca20227db538' 
  AND token = 'iJ1EzaNYXX4FvIvO3NKOfeikduFLdottTCcd5zBMOL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}