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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab46a0e2fd093b57cb1e1c53f514c4648bb92fd1f7857ad9f4b7bc8895f2ab6f' 
  AND token = '+Y1SjuITn+BTRf6t6SUk5pEna3eRiVs20ipzJlxPMFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}