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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b21faa1f0081add2effb366efa0613d5062659bf1595fc6b0f093dcbab47e8f7' 
  AND token = '3BOxn1V/ZvizTebxcdkEk4ONxmgodAbWoo0/qm9u3vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}