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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53994f392ec3260b493da0a35493efb8a7e5ebbb5ec4a9f68f2bd416b4a7db05' 
  AND token = 'wYmYWzRgtDeoFs6OGtWaHAwAhYD6s5tTdLk4YI5Lci4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}