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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e74e95db4f708c2b5f3839867e8c44e19db6736846c5558a3db0a701b59e9f6' 
  AND token = 'PIpZfN2BM64mccn7QnHA6o+iSfaAG5ESaIwRV2B+nI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}