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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c60e8c090e8b29ea54681f2829caa4484606ab23dbacd25e37e403cc2e8c1f' 
  AND token = '9T2IpVW07d4hbpRRs50mAMBPICyPkZRR5rk3CNtosTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}