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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5df9a8a09976b739ee7b29f31a71050900edc9f044bc585d6ad58476bb119fd' 
  AND token = 'cxQiGBKmHLVOAgOzQf7OmXWfxO+KEKQq2emkxfa84gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}