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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52481efaf7c55e5b30e1ff5446d573799f51bc9ce3c4d684f0d6f7d2aa180b51' 
  AND token = 'HmaJ2ysI1THdcskX8L57fOvhyVHQx5WC76kGJKB5uuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}