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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10aa144785bac86376f74e82bf5f412a2decbcc6c6c4976c17aaf23a02c0a84d' 
  AND token = 'JDiF8xQC4jbzMvhBPGT2FgPd9lc1aK6D0kKHFv7anMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}