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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bd73cdf35dc00cccea5f6d25523e47890050a3bd9b263c6b39ae9a45c11a39a' 
  AND token = 'UhfZfydm4FPRGmrjF2mj5jA+B/JU7ZuL890iI12xuY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}