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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53943f421d41a2a78cc08653d0ed5614b18e55904e7caa1d33821185c787435d' 
  AND token = '6PAaBDgo16IBzR4GjjQUAqtaDx9VJ0sQ8Q5/TIsrewA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}