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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '709ae9c04986b67be21936a3ac2cbae08f5bb635f9ceb5333a39f92609177bb5' 
  AND token = 'VwYsBPOvjSUov1J0wLyeiSDi33K0kUEo7oRL0g5QGfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}